Peanut allergen reaction thresholds during controlled food challenges in 2 Canadian randomized studies (Canada-ARM1 and PISCES)

Food allergy affects millions worldwide.1 Vigilance by affected individuals and families is necessary to prevent accidental ingestions, allergic reactions, anaphylaxis. Understanding the minimum amount of food allergen that elicits a reaction—thresholds—in susceptible paramount inform safe practice, manufacturing, public health policy.1 Thresholds can also how optimize challenge schedules, advise patients about potential for design desensitization approaches.